中药炮制对药性和临床疗效的影响

Influence of Chinese Medicine Processing on Drug Property and Clinical Curative Effect

目的探讨中药炮制对药性及临床疗效的影响。方法选取2017年2月—2018年6月收治的脾胃虚寒型功能性消化不良患者130例,分为观察组(经过炮制的中药)和对照组(经过一般修制的中药),各65例,比较2组患者在临床疗效上的差异。结果与对照组相比,观察组患者的治疗有效率(93.85%>81.54%)相对更高(P<0.05),不良反应发生率(6.15%<13.85%)相对更低(P<0.05),而上腹痛缓解时间[(4.39±1.02)d<(6.85±1.38)d]、嗳气症状缓解时间[(3.92±0.85)d<(7.14±1.59)d]以及恶心呕吐缓解时间[(3.85±0.91)d<(6.92±1.33)d]相对更短(P<0.05)。结论中药炮制对于药性具有调节的作用,可以根据临床治疗的需要,合理进行选择,进而提升其临床疗效。

Objective To investigate the effect of Chinese medicine processing on the property and clinical efficacy. Methods 130 patients with functional dyspepsia of deficiency-cold type of spleen and stomach were selected from February 2017 to June 2018. Patients were divided into observation group (processed Chinese medicine) and control group (traditional Chinese medicine) averagely. Their clinical effect was compared. Results Compared with control group, the effective rate of treatment (93.85%>81.54%) in observation group was higher (P<0.05), the incidence of adverse reactions (6.15%<13.85%) was lower (P<0.05), and the relief time of upper abdominal pain [(4.39±1.02)d<(6.85±1.38)d], the relief time of belching symptoms [(3.92±0.85)d <(7.14±1.59)d]. The remission time of nausea and vomiting [(3.85±0.91)d<6.92±1.33)d] was shorter than that of nausea and vomiting (P < 0.05). Conclusion Processing of traditional Chinese medicine has a regulatory effect on drug properties. It can be reasonably selected according to the needs of clinical treatment, and then improve its clinical efficacy.