综合心理护理干预对肝豆状核变性患者抑郁及生活质量的影响

Effect of comprehensive psychological nursing intervention on depression and quality of life in patients with hepatolenticular degeneration

目的调查肝豆状核变性患者的抑郁状况及生活质量,干预以缓解其抑郁情绪,提高其生活质量。方法将39例研究对象随机分为干预组20例和对照组19例,应用汉密尔顿抑郁量表(HAMD)、世界卫生组织生活质量测定简表(WHOQOL-BREF)评估2组患者抑郁情绪及生活质量。对照组进行常规护理指导,干预组在此基础上进行综合心理护理干预,6周后仍用上述量表评价效果。结果干预前肝豆状核变性患者抑郁情绪阳性率为53.8%,干预前2组间HAMD、WHOQOL BREF评分比较无显著差异;干预后干预组各量表评分改善程度显著优于对照组(P<0.05)。结论肝豆状核变性患者存在抑郁情绪、生活质量较差等的问题。综合心理护理干预可有效改善患者的心理状况,提高其生活质量。

Purpose To investigate the depression and quality of life of patients with hepatolenticular degeneration (HLD). Methods Thirty nine subjects were randomly divided into the intervention group (20 cases) and the control group (19 cases).Hamilton depression scale (HAMD) and whoqol bref were used to evaluate the depression mood and quality of life of the two groups.The control group was given routine nursing guidance,and the intervention group was given comprehensive psychological nursing intervention on this basis.After 6 weeks,the above scale was still used to evaluate the effect. Results Before intervention,the positive rate of depression in patients with HLD was 53.8%,and there was no significant difference in HAMD and whoqol bref scores between the two groups before intervention.After intervention,the improvement of scale score in the intervention group was significantly better than that in the control group ( P <0.05). Conclusion Patients with hepatolenticular degeneration suffer from depression and poor quality of life.Comprehensive psychological nursing intervention can effectively improve the psychological status of patients,improve their quality of life.