分析消化性溃疡患者采用小柴胡汤加减治疗的临床效果

Efficacy of the Xiaochaihu decoction on peptic ulcer

目的:分析消化性溃疡患者采用小柴胡汤加减治疗的临床效果。方法:选取2016年2月-2017年2月间在我院进行治疗的消化性溃疡患者112例,采用随机数法按1∶1的比例,将患者随机分为观察组(56例)和对照组(56例)。对照组患者单独使用常规西医治疗,观察组患者采用小柴胡汤加减法进行治疗。观察并对比两组患者临床疗效,治疗后的临床症状(呕吐、疼痛、反酸、腹胀等)发生率和幽门螺旋杆菌转阴率,不良反应情况(头晕、恶心、便秘)的发生率。结果:观察组患者治疗总有效率高于对照组患者,组间差异显著,有统计学意义(P<0.05);治疗后观察组患者呕吐、疼痛、反酸、腹胀发生率均低于对照组患者,组间差异显著,有统计学意义(P<0.05);观察组幽门螺旋杆菌转阴率高于对照组患者,组间差异显著,有统计学意义(P<0.05);观察组患者不良反应发生率低于对照组患者,组间存在显著的统计学差异(P<0.05)。结论:小柴胡汤加减法治疗消化性溃疡患者较常规西医治疗疗效更佳,临床症状得到有效改善,此外,小柴胡汤加减法可显著降低幽门螺旋杆菌感染情况和不良反应发生率,值得在临床上进一步推广和应用。

Objective:To analyze clinical efficacy of the Xiaochaihu decoction (小柴胡汤) on peptic ulcer.Methods:February 2016 - February 2017,112 cases were divided into two groups,56 cases in each.The control group was given conventional western medicine;and the observation group was given the Xiaochaihu decoction.Results:The total efficiency in the observation group was higher than that in the control group (P<0.05).After treatment,the incidence of vomiting,pain,acid reflux and abdominal distension in the observation group were lower than those in the control group (P<0.05).The conversion rate of Helicobacter pylori in the observation group was higher than that in the control group (P<0.05).The incidence of adverse reactions in the observation group was lower than that in the control group (P<0.05).Conclusion:The Xiaochaihu decoction on peptic ulcer showed a good effect,can significantly reduce the incidence of Helicobacter pylori infection and the incidence of adverse reactions,which is worthy of clinical promotion.