老年下呼吸道感染革兰阴性杆菌分布及耐药性分析

Distribution and drug resistance of Gram-negative bacilli in elderly patients with lower respiratory tract infection

目的探究老年下呼吸道感染革兰阴性杆菌分布与耐药心性。方法选取本院2018年2月-2018年11月确诊的老年下呼吸道感染患者,在合格痰液标本中对病原菌进行分离。结果痰液培养标本总计分离出225株病原菌,其中革兰阴性菌164株,所占比例72.89%,包括肺炎克雷伯菌(61株)、大肠埃希菌(35株)、铜绿假单胞菌(28株)、鲍曼不动杆菌(19株)、其他革兰阳性菌(21株),病原菌对常用抗菌药物有了耐药性。革兰阴性菌中肺炎克雷伯菌对氨苄西林的耐药率最高,为95.08%,其次为庆大霉素的耐药率为83.61%,亚胺培南的耐药率为0。结论老年下呼吸道感染主要表现为革兰阴性菌,临床需按照药敏结果科学采用抗菌药。

Objective To investigate the distribution and resistance of Gram-negative bacilli (Gram-negative bacilli) in elderly patients with lower respiratory tract infection. Methods The aged patients with lower respiratory tract infection from Feb. 2018 to Nov. 2018 in our hospital were selected and the pathogens were isolated from qualified sputum samples. Results A total of 225 strains of pathogenic bacteria were isolated from sputum culture samples, of which 164 strains were Gram-negative bacteria (72.89%), including Klebsiella pneumoniae (61 strains), Escherichia coli (35 strains), Pseudomonas aeruginosa (28 strains) and Klebsiella pneumoniae (61 strains), Escherichia coli (35 strains) and Pseudomonas aeruginosa (28 strains). Acinetobacter baumannii (19 strains), other gram-positive bacteria (21 strains). The drug has developed resistance. Among Gram-negative bacteria, Klebsiella pneumoniae had the highest resistance to ampicillin (95.08%), followed by gentamicin (83.61%) and imipenem (0). Conclusion Gram-negative bacteria are the main manifestations of lower respiratory tract infection in the elderly, and antibiotics should be used scientifically according to the results of drug sensitivity.