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胃癌患者血清p53蛋白抗原检测及意义探究 被引量:1

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摘要 目的分析胃癌患者检测血清p53蛋白抗原的方法与临床意义。方法选择我院2018年1月-2018年12月48例胃癌患者和同期非胃癌患者50例进行血清p53蛋白抗原检测,将检测结果进行对比分析。结果48例胃癌患者血清p53蛋白含量为(14.7±8.19)U/L,同期50例非胃癌患者血清p53蛋白含量为(6.11±3.84)U/L,胃癌患者血清p53蛋白含量显著高于非胃癌患者(P<0.01);48例胃癌患者阳性率为33.33%(16/48),50例非胃癌患者阳性率为4.0%(2/50)。对48例胃癌患者中12例手术患者血清p53蛋白进行动态观察,术后7d,12例患者术后7d血清p53蛋白抗原检测结果为阳性,术后30d血清p53蛋白含量显著下降,术后90d血清p53蛋白抗原检测结果为阴性。结论血清p53蛋白抗原检测对于预测胃癌患者有无p53蛋白异常表达具有重要意义,可以用于胃癌血清学辅助诊断。
作者 张元
出处 《临床检验杂志(电子版)》 2019年第4期116-117,共2页 Clinical Laboratory Journal(Electronic Edition)
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