儿童非紫绀型先天性心脏病体外循环术后急性肾损伤相关危险因素分析

Analysis on risk factors for acute kidney injury after cardiopulmonary bypass in children with non-cyanotic congenital heart disease

目的对儿童非紫绀型先天性心脏病体外循环术后急性肾损伤(AKI)相关危险因素进行分析。方法选取2018年1~12月我院收治的非紫绀型先天性心脏病体外循环的患儿300例,根据术后是否发生急性肾损伤,将患儿分为AKI组(62例)和非AKI组(238例),收集患儿的相关临床资料,比较两组患儿间临床指标的不同,采用多因素Logistic回归分析体外循环术后急性肾损伤相关危险因素。结果年龄、肺炎和(或)心力衰竭史、体外循环时间、主动脉阻断时间和术后机械通气时间是术后发生急性肾损伤的危险因素。结论可通过避免或降低筛选出的危险因素来降低术后急性肾损伤的发生率。

Objective To analyze risk factors for acute kidney injury after cardiopulmonary bypass in children with non-cyanotic congenital heart disease. Methods 300 children with non-cyanotic congenital heart disease who underwent cardiopulmonary bypass in our hospital from January 2018 to December 2018 were selected. Children were divided into AKI group(62 cases) and non-AKI group(238 cases) according to whether acute kidney injury occurred after operation. The relevant clinical data of the children were collected and the differences in clinical indexes between the two groups were compared. Multivariate logistic regression was used to analyze the risk factors associated with acute kidney injury after cardiopulmonary bypass. Results Age, history of pneumonia and/or heart failure, time for cardiopulmonary bypass, time of aortic occlusion and time of postoperative mechanical ventilation were risk factors for acute renal injury after operation. Conclusion The incidence of postoperative acute kidney injury can be reduced by avoiding or reducing the selected risk factors.