乳腺增生症的中医体质分布及其相关发病因素与体质分型的相关性研究

Study on the correlation between constitution distribution of traditional Chinese medicine and its related pathogenic factors and constitution types of mammary gland hyperplasia

目的研究乳腺增生症患者的中医体质类型分布情况,并对其相关发病因素与体质类型的相关性进行探讨。方法选取乳腺增生症女性患者250例作为研究组,另选取同一时期体检健康的女性212例作为健康对照组进行病例对照研究。2组研究对象入组后均按要求填写《中医体质分类与判定表》,并对其体质类型进行判定,研究组患者还需填写自拟的《乳腺增生症临床调查表》,对比分析乳腺增生症患者临床主要的中医体质类型表现及不同体质类型与乳腺增生症相关发病因素(包括年龄、性格偏向、饮食偏好及工作性质)的相关性。结果乳腺增生症患者中医体质类型由高分布到低依次是气郁质、痰湿质、瘀血质、阳虚质、阴虚质等,其中研究组阳虚质、痰湿质、瘀血质及气郁质患者均明显多于健康对照组(P<0.05),是乳腺增生症的4种常见体质类型;乳腺增生症4种常见体质类型中阳虚质的分布特点是年龄51~60岁、性格偏向急躁易怒、饮食偏好素食及非体力工作(均P<0.05),痰湿质的分布特点是年龄31~50岁、性格偏向开朗或温和、饮食偏好荤食及非体力工作(均P<0.05),瘀血质的分布特点是年龄31~50岁、性格偏向急躁易怒、饮食偏好荤食及非体力工作(均P<0.05),气郁质的分布特点是年龄20~40岁,性格偏向急躁易怒、饮食偏好荤食及非体力工作(均P<0.05)。结论乳腺增生症患者的不同中医体质类型分布存在一定差异,临床中以阳虚质、痰湿质、瘀血质及气郁质的偏颇体质最常见,且不同体质类型与患者的年龄、性格偏向、饮食偏好及工作性质存在一定相关性。

Objective To study the distribution of constitutional types of traditional Chinese medicine in patients with mammary gland hyperplasia, and to explore the correlation between the related pathogenic factors and constitutional types. Methods 250 female patients with mammary gland hyperplasia were selected as the study group, and 212 healthy women in the same period were selected as the healthy control group for case-control study. Two groups of subjects were asked to fill in the "classification and judgment form of traditional Chinese medicine constitution" and determine their constitution types. The study group also needed to fill in the self-made "clinical questionnaire of mammary gland hyperplasia". To compare and analyze the clinical manifestations of main traditional Chinese medicine constitution types in patients with mammary gland hyperplasia and the correlation between different constitution types and the related factors of mammary gland hyperplasia(including age, personality bias, dietary preference and working nature). Results The traditional Chinese medicine constitution types of patients with mammary gland hyperplasia were qi stagnation, phlegm dampness, blood stasis, yang deficiency and yin deficiency in order from high to low.The patients with yang deficiency,phlegm dampness,blood stasis and qi stagnation in the study group were significantly more than those in the healthy control group(P<0.05), which were the four common constitution types of mammary gland hyperplasia. Among the four common constitutional types of mammary gland hyperplasia, the distribution characteristics of yang deficiency were age range of 51-60 years, the personality tend to be irritability, and dietary preference for vegetarian food and non-physical work(all P<0.05). The distribution characteristics of phlegm dampness were age range of 31-50 years, the personality tend to be cheerful or mild, and dietary preference for meat and non-physical work(all P<0.05). The distribution characteristics of blood stasis were age range of 31-50 years, the personality tend to be irritability, and dietary preference for meat and non-physical work(all P<0.05). The distribution characteristics of qi stagnation were age range of 20-40 years, the personality tend to be irritability, and dietary preference for meat and non-physical work(all P<0.05). Conclusion There are some differences in the distribution of different traditional Chinese medicine constitution types in patients with mammary gland hyperplasia. The biased constitution of yang deficiency, phlegm dampness, blood stasis and qi stagnation is the most common constitution in clinic, and there are certain correlations between different physical types and patients’ age, personality bias, dietary preferences and work nature.