米非司酮配伍米索前列醇用于高危产妇终止妊娠的临床效果分析

Clinical Effect of Mifepristone Combined with Misoprostol on Termination of Pregnancy in High-risk Parturients

目的:探讨分析米非司酮配伍米索前列醇用于高危产妇终止妊娠的临床效果。方法:在我院收治的需要终止妊娠的高危产妇中抽取40例作为研究对象,按照治疗方式的不同将40例入组患者分为对照组(n=20)与研究组(n=20),对照组采用羊膜穿刺术进行100mg利凡诺注入,研究组口服米非司酮+米索前列醇,比较2组流产效果及不良反应。结果:研究组完全流产率高于对照组,流产失败率低于对照组(P<0.05);且两组不良反应总发生率比较无差异(P>0.05)。结论:给予需要终止妊娠的高危产妇应用米非司酮配伍前列醇能够有效提高完全流产率,安全有效,值得临床推广应用。

Objective:To investigate the clinical effect of mifepristone combined with misoprostol for termination of pregnancy in high-risk women.Methods:Forty high-risk women who needed termination of pregnancy in our hospital were enrolled as subjects.According to different treatment methods,40 patients were divided into control group(n=20)and study group(n=20).The control group was treated with amniocentesis for 100 mg rivanol injection.The study group received oral mifepristone+misoprostol,and the effects of two groups of abortion and adverse reactions were compared.Results:The complete rate of abortion in the study group was higher than that in the control group.The failure rate of abortion was lower than that in the control group(P<0.05).There was no difference in the total incidence of adverse reactions between the two groups(P>0.05).Conclusion:The application of mifepristone and prostaglandin in high-risk women who need to terminate pregnancy can effectively improve the complete abortion rate,safe and effective,and is worthy of clinical application.