肝硬化合并胆管结石的临床特征分析

The clinical analysis of the features of cirrhosis with cholangiolithiasis

目的探讨肝硬化合并胆管结石患者的肝硬化临床特征.方法收集我院2012年4月至2017年4月入院治疗的119例肝硬化合并胆管结石患者的临床资料,1:1匹配选取119例肝硬化无胆管结石患者作为对照组.比较两组患者的肝硬化病因、肝功能、门脉高压症、肝硬化并发症发生率的差异.结果肝硬化合并胆管结石主要病因是胆汁淤积,肝功能损伤明显,门脉高压症中脾亢发生率更高,总体并发症发生率低于无胆管结石的肝硬化患者.结论分析肝硬化合并胆管结石患者的临床特征有助于肝硬化合并胆管结石患者的诊治.

Objective To investigate the clinical features of cirrhosis in cirrhosis patients with cholangiolithiasis. Methods Clinical data of 119 cirrhosis patients with cholangiolithiasis who were admitted to the 1st Affiliated Hospital of Anhui Medical University from April 2012 to April 2017 was collected, while 119 cirrhosis patients without biliary stone were selected as the control group. The etiology of cirrhosis, liver function, portal hypertension, and the incidence of complications of cirrhosis were compared between the two groups. Results The main etiology of cirrhosis with biliary stone was cholestasis, and the liver function was damaged more obviously and the incidence of hypersplenism was higher in the cirrhosis patients with biliary stone. The overall complication rate of cirrhosis patients with cholangiolithiasis was lower than that of cirrhosis patients without cholangiolithiasis. Conclusion It is helpful to investigate the clinical features of cirrhosis patients with cholangiolithiasis in diagnosis and treatment of cirrhosis patients with cirrhosis with biliary stone.