摘要
The ovum oil of forest frog has various health beneficial functions.In the current research,we evaluated the hypolipidemic effects of the low-cholesterol ovum oil from the forest frog and its combination with stigmasterol in rats.
目的:探索林蛙副产物林蛙卵油的开发价值。创新点:首次验证了低胆固醇林蛙卵油的减重降脂功能。方法:Sprague-Dawley大鼠连续被灌胃8周后,分成8组:(1)对照组喂食标准饲料;(2)高脂组喂食60%高脂饲料;(3)阳性对照组喂食3.33 mg/(kg·d)辛伐他汀;(4)OORC组喂食2 g/(kg·d)的低胆固醇林蛙卵油(OORC);(5)植物甾醇组喂食0.48g/(kg·d)的豆甾醇;(6)低剂量组喂食1g/(kg·d)的低胆固醇OORC和0.24g/(kg·d)的豆甾醇;(7)中剂量组喂食2g/(kg·d)的低胆固醇OORC和0.48 g/(kg·d)的豆甾醇;(8)高剂量组喂食4 g/(kg·d)的低胆固醇OORC和0.96 g/(kg·d)的豆甾醇。经过不同方法处理后,比较各组大鼠的体重、器官指数,以及血清中总胆固醇、甘油三酯、低密度脂蛋白和高密度脂蛋白浓度。同时,对动物肝脏进行组织切片染色并评价损伤情况。结论:低胆固醇林蛙卵油或者其与植物甾醇(如豆甾醇)联用可以预防高脂饮食诱导的增重、肝损伤和高血脂症状。
基金
Project supported by the Jilin Province Research and Industrialization with Key Technologies for High Value Processing and Safety Control of Agricultural Products(No.SF2017-6-4)
the Jilin Provincial Department of Education(No.JJKH20180172KJ),China
