植物转录调控因子NF-Y研究进展

Recent Advances in Plant Transcription Factor NF-Y

NF-Y是在植物、动物和酵母细胞均存在的转录调节因子,由NF-YA、NF-YB以及NY-YC组成异源三聚体,在细胞核内结合在下游基因启动子上调节基因转录活性,或通过与核内其它蛋白的互作调节细胞生命活动.NF-YA(核因子Y,亚基A)是具有多种生物功能的植物转录调控因子,其与NF-YB、NF-YC组成异源三聚体,结合下游基因的CCAAT顺式元件,从而激活或抑制一些基因的表达.NF-YA、NF-YB和NF-YC参与植物体内许多生理过程,包括胚胎发育、种子发育及萌发、花的发育、根和根瘤发育以及各种逆境反应等重要的生理过程.本文就植物中转录调控因子NF-YA、NF-YB和NF-YC的基本结构特点、生物学功能,以及它们在植物响应生物和非生物胁迫方面的作用进行了综述.

NF-Y (nuclear factor Y) is an important transcription factor in plant, animal and yeast cells. It is generally composed of NF-YA, NF-YB and NF-YC, which is a heterotrimer that binds to the promoter of downstream gene in the nucleus to regulate the transcriptional activity, or regulating the cellular life activities by interaction with other proteins in the nucleus. NF-YA (nuclear factor Y, subunit A) is a transcription factor with multiple biological functions, which forms a heterotrimer together with NF-YB and NF-YC, thereby activating or inhibiting the expression of related genes via binding with the CCAAT motif of the downstream genes. NF-YA, NF-YB and NF-YC are involved in many physiological processes in plants, including embryo development, seed development and germination, flower development, root and nodule development and various stress responses. This article reviewed the basic structural features and the biological functions of the transcription factors NF-YA, NF-YB and NF-YC, as well as their roles in plant responses to biotic and abiotic stress.