三维全容积成像技术评价不同年龄正常成人左心室容积及收缩功能

Three-dimensional full-volume imaging was used to evaluate the left ventricular volume and contractile function of normal adults in different ages

目的:应用全容积成像(Full-volume imaging,FVI)技术对不同年龄段正常成人左心室容积同步性及心室收缩功能进行检测,探讨年龄对其的影响。方法:将我院健康体检中心查体的126例健康成人按年龄分为青年组(43例,男21例女22例,年龄18~45岁)、中年组(42例,男20例女22例,年龄46~64岁)和老年组(41例,男22例女19例,年龄≥65岁)。常规超声心动图检查后获取常规超声测值,连接心电图后用4V探头采集动态心尖四腔心切面,获取左心室全容积图像行FVI在线分析。结果:与青年组相比,中年组、老年组M型超声射血分数(EF)测值随着年龄的增加逐渐减低,差异有统计学意义(P<0.05);与青年组相比,中年组、老年组每搏输出量(SV)随着年龄的增加逐渐减低,差异均有统计学意义(P<0.05);全容积EF测值三组之间随着年龄的增加而减低,这与M型测值具有相关性,相关系数为0.415,与青年组、中年组相比,老年组收缩期失同步指数(SDI)、收缩末离散度/差(DISPES)、收缩前时间容积(Pre Contr)差异有统计学意义(P<0.05),表现为增高。结论:随着年龄的增加,EF值逐渐减低,左心室收缩期失同步性风险逐渐增高。

Objective: Full-volume imaging (FVI) was used to detect the synchronism of left ventricular volume and ventricular systolic function in normal adults of different ages, and to explore the influence of age on it. Methods: In the hospital physical exami nation center, there were 126 healthy adults on examination who were divided into the youth group(43 cases, 21 male and 22 female, age 18~45 years old), the middle-aged group (42 cases, 22 male and 20 female, 46~64 years old) and elderly group(41 cases, 22 male and 19 female, age 65 years old or higher) by age. After routine echocardiography, conventional echocardiography values were obtained. After connecting with the electrocardiogram, a 4V probe was used to collect the dynamic four-chamber cardiotomy surface of the apex of the heart and obtain the full-volume image of the left ventricle for online with FVI analysis. Results: Compared with the youth group, the measured values of M-type ultrasound ejection fraction(EF) in the middle-aged and elderly groups gradually decreased with the increase of age, and the difference was statistically significant (P<0.05). Compared with the youth group, the SV of each stroke in the middle-aged group and the elderly group gradually decreased with the increase of age, and the difference was statistically significant (P<0.05). The total volume EF measured value decreases with age, which is related to the M-type measured value. The correlation coefficient is 0.415. Compared with young and middle-aged group, the systolic dyssynchrony index (SDI), dispersion in end systole (DISPES), precontraction time volume (Pre Contr) was statistically increased in elderly group(P<0.05). Conclusion: As the age increases, the EF value decreases and the risk of left ventricular systolic dyssynchrony increases.