新型快速病理诊断技术在超声引导下甲状腺癌穿刺检查中应用的临床价值探讨

Clinical value of application of new rapid pathological diagnosis technology in ultrasound-guided puncture in thyroid cancer

目的 探讨新型快速病理诊断技术在甲状腺癌穿刺检查中应用的临床价值。方法 选择本院2017年7月至2018年6月期间术前倾向于甲状腺癌且经术后病理证实的甲状腺穿刺患者12例,其中8例采用US-FNA检查,4例采用US-CNB检查,在甲状腺穿刺操作过程中采用新型快速病理诊断技术进行实时细胞学初诊,并依据快速病理诊断结果实时调整穿刺操作方案,分析新型快速病理诊断技术在甲状腺癌穿刺检查中的临床价值。结果 新型快速病理诊断技术开展所需空间小,无污染,诊断耗时2~3min,不影响正常穿刺操作。8例US-FNA中的2例(25.0%)与4例US-CNB中的1例(25.0%)在本技术协助下达到穿刺操作对肿瘤成分质与量的要求。结论 确诊甲状腺癌的US-FNA检查或US-CNB检查,均会因多种因素的干扰而影响到诊断的质量。新型快速病理诊断技术在可甲状腺穿刺过程中提供实时病理诊断,以此确保穿刺组织中肿瘤成分的质与量,保证甲状腺穿刺的首次成功率,且本技术开展成本低,适宜在各级医院推广施行。

Objective To explore the clinical value of applying new rapid pathological diagnosis technology in ultrasound-guided puncture in thyroid cancer.Methods Twelve patients taking thyroid puncture who preoperatively tended to have thyroid cancer and were confirmed by postoperative pathology were selected.Among which,8 cases were examined with US-FNA,and 4 with US-CNB.The new rapid pathological diagnosis technique was used during thyroid puncture operation.Real-time cytology was first diagnosed and the puncture operation plan was adjusted in real time according to the results of rapid pathological diagnosis.The clinical value of new rapid pathological diagnosis technique in thyroid cancer puncture was analyzed.Results The new rapid pathological diagnosis technology required a small space and had no pollution.The diagnosis took about 2 to 3 minutes and did not affect the normal puncture biopsy operation.2 cases(25.0%)of the 8 taking US-FNAs and 1 case(25.0%)of the 4 taking US-CNBs with the assistance of this technology confirmed the requirement of biopsy quality and quantity.Conclusion Because of various factors,the quality and quantity of biopsy tissue are often not guaranteed in the US-FNA or US-CNB tests.The new rapid pathological diagnosis technology can provide real-time pathological diagnosis during thyroid puncture and improve the quality and quantity of puncture tissue,and ensure the first success rate of thyroid puncture;and the cost of this technology is low;so it is suitable for implementation in hospitals at all levels.