三七茎对家兔实验性高脂血症的影响

The Effect of the Panax Notoginseng Stalks on Experimental Hyperlipidemia of Rabbits

目的:探究三七茎对家兔实验性高脂血症的影响。方法:将家兔随机分为4组,除对照组外,其余组加喂猪油和胆固醇,并对低剂量组和高剂量组喂以不同剂量的三七茎,利用酶学终点法于给药前和给药后2,4,6周测定其TC、TG、HDL-C、LDL-C值。结果:与对照组比较,高脂组家兔的TC、TG、LDL-C值升高,HDL-C值降低,差异有统计学意义(P<0.05)。与高脂组比较,低剂量组和高剂量组的TC、TG、LDL-C值降低,HDL-C值升高,差异有统计学意义(P<0.05)。结论:三七茎对实验性高脂血症家兔具有降血脂作用。

Objective:To explore the effect of the Panax notoginseng stalks on experimental hyperlipidemia of rabbits.Methods:Rabbits were randomly divided into four groups,besides the control group,the rest of the group were fed with lard oil and cholesterol,the low-dose group and the high-dose group were fed with different doses of Panax notoginseng stalks.Then measuring the TC、TG、HDL-C、LDL-C values before administration and 2 nd,4 th,6 th week after administration by enzyme terminal method.Results:Compared with the control group,the TC、TG and LDL-C values in the high-fat group were increased,and the HDL-C value decreased,the difference was statistically significant(P<0.05).Compared with the high-fat group,the TC、TG、LDL-C values of the low-dose group and the high-dose group decreased,and the HDL-C value increased,the difference was statistically significant(P<0.05).Conclusion:Panax notoginseng stalks have the effect of lowering blood lipids on experimental hyperlipidemia of rabbits.