摘要
布鲁氏菌引起的布鲁氏菌病是一种严重危害人畜健康的传染性疾病,采用疫苗防治该菌是当前研究的热点领域之一。OMP、SOD和L7/L12抗原是3种有效的疫苗候选分子,本文综述了鼠伤寒沙门氏菌、乳酸乳球菌、卡介苗、人赭菌、根癌农杆菌、大肠埃希菌、小肠结肠耶尔森菌、毕赤酵母、禽流感病毒、Semliki森林病毒、山羊痘病毒、牛痘病毒、腺病毒血清型5、伪狂犬病毒和昆虫杆状病毒等载体介导的布鲁氏菌疫苗的研制现状。
Brucellosis caused by Brucella is one type of infectious diseases seriously endandering human and animal health,it recently becomes highlight to control this bacteria by use of the vaccine.OMP,SOD and L7/L12 antigen are 3 types of effective candidate molecules of vaccine,the review outlines the status in the research of vaccine of Brucella mediated by bacteria such as Salmonella typhimurium,Lactococcus lactis,Bacille calmette-Guerin,Ochrobactrum anthropi,Agrobacterium tumefacies,Escherichia coli,Yersinia enterocolitica,and Pichia pastoris,viruses such as Avian Influenza Virus,Semliki forest virus,Goat poxvirus,Vaccinia virus,Adenovirus serotype 5,Pseudorabies Virus,and Baculovirus.
作者
李文桂
陈雅棠
LI Wengui;CHEN Yatang(Institute of Infectious and Parasitic Diseases,the First Affiliated Hospital,Chongqing Medical University,Chongqing 400016,China)
出处
《国外医学（医学地理分册）》
CAS
2019年第2期97-104,共8页
Foreign Medical Sciences：Section of Medgeography
基金
国家自然科学基金资助项目(30801052、30671835、30500423、30200239)
