乙型流感病毒相关的儿童急性坏死性脑病一例报道并文献复习

Successful Treatment of Influenza B-associated Acute Necrotizing Encephalopathy of Childhood:a Case Report and Literature Review

急性坏死性脑病(ANE)是一种以双侧丘脑病变为特征的罕见急性脑病,多继发于病毒感染,其中流感病毒是最常见的病原体。ANE的预后通常较差,病死率高,常有神经系统后遗症。本文报道了1例得到成功诊治的乙型流感病毒相关的ANE患儿的诊治过程,并对相关文献进行了复习,以提高临床医生对该罕见疾病的认识,为临床工作提供借鉴。

Acute necrotizing encephalopathy(ANE) is a rare acute encephalopathy of brain characterized by bilateral thalamic lesions,and develops secondarily to viral infections.Influenza viruses are the most common etiological agents of ANE.The prognosis of ANE is usually poor with a high mortality rate and neurological sequelae.In this paper,we reported our clinical diagnosis and successful treatment of a case with influenza B-associated ANE of childhood.And the relevant literature was reviewed to improve the awareness of this rare disease and provide reference for clinical work.