卵形家族蛋白对植物生长发育的调控作用

Regulatory Roles of Ovate Family Proteins on Plant Growth and Development

卵形家族蛋白(ovate family proteins, OFPs)是仅存在于植物且具有保守OVATE结构域的一类转录抑制因子。Ovate最早在番茄中克隆并定位于2号染色体上。GTA496-TTA493的单核苷酸突变使得终止密码子提早出现而导致果实由圆形变为梨形。后来在拟南芥、水稻、辣椒、香蕉等植物中陆续开展了其功能研究。发现它是通过直接调控靶基因的表达或者与其它转录因子的相互作用来调控植物生长发育过程的。本文综述了其对果实形状、果实成熟及品质形成、胚珠发育、维管束发育、次生细胞壁的形成等方面的研究进展及可能的调控作用机制,以期为采用生物技术手段利用该蛋白调控植物生长发育提供理论依据。

Ovate family proteins(OFPs) is a class of transcription suppressor, which exist only in the plant with a conserved OVATE domain. Ovate was first cloned in tomato and mapped to chromosome 2. The single GTA496-to-TTA493 nucleotide polymorphism mutation created an early stop codon in the ovate genotype, leading to the change of round-shaped to pear-shaped fruit. Then, the functions of OFPs were successively investigated in Arabidopsis, rice, pepper and banana. It was found that OFPs can regulate plant growth and development by directly regulating the expressions of target genes or interacting with other transcription factors. This article reviewed the functions and regulatory mechanisms of OFPs on fruit shape, fruit ripening and quality formation, ovule development, vascular development and secondary cell wall formation in recent years, which hoped to provide a theoretical basis for utilizing OFPs to regulate plant growth and development through biotechnology tools.