苦地丁的化学成分研究

Study on the chemical constituents of Corydalis bungeana

目的研究苦地丁乙醇提取物中的化学成分。方法利用萃取和硅胶柱层析分离和纯化苦地丁乙醇提取物,对分离得到的化合物进行理化性质表征和波谱结构鉴定。结果从苦地丁乙醇提取物中分离得到7个化合物,分别鉴定为:二氢血根碱(Ⅰ)、乙酰紫堇灵(Ⅱ)、血根碱(Ⅲ)、紫堇灵(Ⅳ)、原阿片碱(Ⅴ)、延胡索乙素(Ⅵ)、1,2,3,4,4α,9β-hexahydro-5-(4-methoxy-1,4-dioxobutyl)-2,2,8-trimethyl.

OBJECTIVE To study the chemical constituents of the ethanol extract of Corydalis bungeana Turcz.METHODS The ethanol extract of C.bungeana was isolated and purified using various methods such as extraction and silica gel column chromatography.The physicochemical properties and spectral structure identification of the isolated compounds were performed.RESULTS Seven compounds were isolated from the ethanol extract of C.bungeana and identified as:Dihydrogen root base(Ⅰ),acetyl purpurin(Ⅱ),root alkaloids(Ⅲ),purpurin(Ⅳ),protopine(Ⅴ),tetrahydropalmatine(Ⅵ),1,2,3,4,4α,9β-hexahydro-5-(4-methoxy-1,4-dioxobutyl)-2,2,8-trimethyl-,(4αS,9βR)-5H-pyrido[4,3-b]indolium.(Ⅶ).CONCLUSION CompoundⅦis isolated from this plant for the first time.