中医药防治手足口病文献分析

Literature Analysis on Prevention and Treatment of Hand-Foot-Mouth Disease with Traditional Chinese Medicine

目的:通过分析中医药防治手足口病的文献,了解中医药防治手足口病的历史概况及用药规律。方法:检索中国知网资源数据库、维普期刊全文数据库、中国生物医学文献数据库、中国中医药期刊文献数据库、中国医药学术会议论文全文数据库及万方信息资源系统,从文献的分布年代、中药使用频率、功效分类及证型分布等方面对手足口病进行分析研究。结果:①分布年代:中医药防治手足口病的文献始见于1985年,从2005年开始,相关文献迅速增多。②中药使用频率:防治手足口病的中药共104味,用药5次及以上的药物共有42味,使用频次前5位为金银花、连翘、甘草、黄芩及石膏。③药物功效:清热药最多,其中又以清热解毒、清热泻火、清热凉血居多;解表药次之,其中又以发散风热居多;化湿药7味。④证型分类:共分为10个证型,以邪犯肺卫证最多;湿重于热证次之;肺脾湿热证第3。结论:中医药防治手足口病具有显著优势,治疗上主要进行辨证分型分期论治,以清热解毒、凉血透疹中药为主,注重热、湿、风、痰等邪气的祛除,从而达到标本共治。

Objective:To analyze the literature on prevention and treatment of hand-foot-mouth disease with Chinese medicine in the past 66 years,and to understand the historical situation and the law of drug use of traditional Chinese medicine for prevention and treatment of the disease.Methods:Retrieving China Knowledge Network Resource Database,Weipu Journal Full-text Database,China Biomedical Literature Database,China Traditional Chinese Medicine Journal Literature Database,China Medical Academic Conference Paper Full-text Database and Wanfang Information Resource System,from the distribution age of the literature,the frequency of Chinese medicine use,the classification of efficacy and the distribution of syndromes,etc.Results:①Distribution age:The literature on prevention and treatment of hand,foot and mouth disease by Chinese medicine was first seen in 1985.Since 2005,the related literature has increased rapidly.②Chinese medicine use frequency:a total of 104 flavors of traditional Chinese medicine for prevention and treatment of hand,foot and mouth disease,a total of 42 flavors of drugs used 5 times or more,the top 5 use frequency is Honeysuckle,Forsythia,Licorice,Scutellaria and Gypsum.③Drug efficacy:the most heat-clearing drugs are those functioning inclearing Heat and detoxification,clearing Heat and purging Fire or clearing Heat and cooling blood;the second place drugs are drugs for relieving exterior disorder,most of which functions to divergent Wind and Heat;④Types of syndromes:There are a total of 10 syndrome types,with the Evil invading Lung Qi and Wei Qi being the most cases;the Dampness Syndrome combined with Heat Syndrome is the second case;the Lung and Spleen Dampness and Heat syndrome is the third case.Conclusion:Traditional Chinese medicine has a significant advantage in the prevention and treatment of hand-foot-mouth disease.The main treatment is to carry out by syndrome differentiation and flexible treatment in different stages.It is mainly used for clearing away heat and detoxifying as well as cooling blood and diarrhea,focusing on the elimination of Heat,Dampness as well as Wind and Phlegm.In this way,both the cause of the disease and the symptoms of the disease can be removed at the same time.