中国高原地区骨质疏松与骨折风险的临床研究进展

Clinical research on osteoporosis and fracture risks in plateau areas in China

骨质疏松症是一种由多因素所致的慢性疾病,与骨质疏松症相关的骨折称为骨质疏松性骨折。目前认为与骨质疏松及骨折有关的因素包括:氧气浓度、日照、身体质量、性别、年龄、外伤、饮食活动习惯、烟酒药物使用及遗传等。在我国西部高原地区,氧气浓度、地势、饮食生活习惯等影响因素较平原地区更为突出。本文就我国高原地区骨质疏松及骨折风险的临床研究进展作一综述,旨在针对不同危险因素提出相应的防治措施,以降低我国高原地区骨质疏松症及骨折的发病率。

Osteoporosis is a chronic disease influenced by multiple factors. The fractures associated with osteoporosis are known as osteoporotic fractures. The factors associated with osteoporosis and fracture include oxygen concentration, sunshine, body mass, gender, age, trauma, dietary habits, tobacco and alcohol use, medical history and inheritance. Factors such as oxygen concentration, topography and dietary habits play a more important role in the western plateau areas in China than in the plain areas. The present study reviews the clinical research on the osteoporosis and fracture risks in the plateau areas in China and proposes prevention and treatment measurements for the risk factors to reduce the incidences of osteoporosis and fracture in the plateau areas.