帕金森病自主神经功能障碍研究进展

Research progress of autonomic dysfunction in Parkinson’s disease

帕金森病是好发于中老年人的神经变性病,自主神经功能障碍是其常见临床症状,严重影响患者生活质量。对帕金森病自主神经功能障碍的流行病学、临床表现、治疗原则及其在早期诊断与鉴别诊断中的意义进行论述,有助于疾病的早期诊断与综合管理。

Parkinson’s disease(PD)is a common neurodegenerative disease in the middle-aged and the elderly.Symptoms of autonomic dysfunction are frequently seen in PD patients,severely affecting the quality of life.This review summarizes research progress on the epidemiology,clinical manifestations,treatment principle,and the significance in early diagnosis and differential diagnosis of autonomic dysfunction in PD patients which helps to the early diagnosis and comprehensive management of PD.