Ag@Parylene-C纳米结构制备技术研究及其SERS性能表征

Preparation of Ag@ Parylene-C Nanostructures and Characterization of SERS

针对二氧化硅包覆材料可重复利用性较差的问题,采用Parylene-C薄膜对银纳米颗粒进行包覆,制备了简易的微流体沟道,并与Ag@Parylene-C纳米结构衬底集成。通过表征Ag@Parylene-C纳米结构衬底对拉曼信号的增强效果及其在液相环境下的稳定性可得出:当沉积的Ag@Parylene-C纳米结构衬底膜厚为100nm时,其包覆效果较好且SERS活性较强,对结晶紫分子的检测限可达10^-10 M。并且通过与微流体沟道集成,其可重复利用次数可以增加到500次,衰减幅度可减小到10%以下,充分证明了Ag@Parylene-C纳米结构SERS基底在微流体检测应用中具有广泛应用前景。

Parylene-C was then deposited on the Ag NPs substrate to deal with the poor reusability of the Ag@SiO 2 substrate.A kind of simple microfluidic channel structure was fabricated and then integrated with the Ag@Parylene-C substrate to test the SERS activity and stability of the substrate in the liquid phase environment.It is found that the Ag@Parylene-C substrate with a thickness of 100 nm showed the fine coating effect and high SERS activity.After integrated with the microfluidic channel structure,the detecting limit of CV molecules that absorbed on Ag@Parylene-C substrate could reach 10^-10 M,and the reused times of the Ag@Parylene-C substrate can be extended from 20 to 500.After the 500 testing experiments,the attenuation on SERS activity of the Ag@Parylene-C substrate is less than 10%.The result indicated that the Ag@Parylene-C substrate can be the candidate for the in-situ microfluidic SERS biochemical sensing application.