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地佐辛复合罗哌卡因对胃癌患者术后镇痛效果和应激反应的影响 被引量:2

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摘要 目的观察地佐辛复合罗哌卡因对胃癌患者术后镇痛效果和应激反应的影响。方法选取2016年6月至2018年8月长征人民医院麻醉科收治的80例胃癌患者作为研究对象,按照随机数表法分为对照组和观察组,各40例。于切皮前10 min给予对照组罗哌卡因进行浸润麻醉,观察组在对照组基础上在手术结束前30 min静注地佐辛,比较两组镇痛效果[视觉模拟评分量表(VAS)评分]和应激反应指标[丙二醛(MDA)、血清皮质醇(Cor)、肾上腺素(E)、去甲肾上腺素(NE)]水平。结果术后各时间点,观察组VAS评分均低于对照组,差异有统计学意义(均P<0.05);术后,观察组各应激反应指标水平均低于对照组,差异有统计学意义(均P<0.05)。结论地佐辛复合罗哌卡因麻醉在胃癌患者术后镇痛中效果显著,且可在一定程度上降低其应激反应水平。
作者 陈艳霞
出处 《河南医学研究》 CAS 2019年第11期2022-2023,共2页 Henan Medical Research
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