甲钴胺治疗糖尿病神经病变临床疗效探讨

Clinical Efficacy of Mecobalamin in the Treatment of Diabetic Neuropathy

目的分析甲钴胺在治疗糖尿病神经病变方面的临床疗效。方法该院2016年1月-2018年1月收治的114例糖尿病患者作为该次研究的选择对象,对其病例资料展开回顾性分析。将患者分为观察组和对照组,每组57例。对照组采用常规治疗方案,包括血糖控制、维生素治疗等。观察组在此基础上使用甲钴胺进行治疗。在治疗结束后比较两组患者的临床疗效,分析甲钴胺的使用价值。结果研究结果表明,在治疗有效率方面观察组的94.7%要显著优于对照组的80.7%,数据差异有统计学意义(χ^2=4.025,P=0.017),证明了甲钴胺的临床价值。结论甲钴胺在糖尿病神经病变的临床疗效显著,为今后神经病变工作提供了重要的治疗方向。

Objective To analyze the clinical efficacy of mecobalamin in the treatment of diabetic neuropathy.Methods 114 patients with diabetes mellitus admitted to our hospital from January 2016 to January 2018 were selected as the study subjects,and their case data were retrospectively analyzed.Patients were divided into observation group and control group,57 cases in each group.The control group used conventional treatment options,including glycemic control,vitamin therapy,and the like.The observation group was treated with methylcobalamin on this basis.The clinical efficacy of the two groups of patients was compared after the end of treatment,and the use value of mecobalamin was analyzed.Results The results of the study showed that 94.7%of the observation group was significantly better than the control group by 80.7%in terms of treatment efficiency.The data were statistically significant(χ^2=4.025,P=0.017),which proved the clinical value of development of mecobalamin.Conclusion The clinical efficacy of mecobalamin in diabetic neuropathy is significant,which provides an important therapeutic direction for future neuropathy work.