综合治疗内分泌失调性骨质疏松症的疗效研究

Therapeutic Effect of Comprehensive Therapy on Endocrine Disorder Osteoporosis

目的探讨综合疗法治疗内分泌失调性骨质疏松症的临床疗效。方法便利选择该院2016年6月—2017年9月收治的内分泌失调性骨质疏松症患者132例,以便利抽样法分为参照组和治疗组各66例,参照组采取常规疗法,治疗组采取综合治疗,对比两组患者临床疗效。结果治疗组总有效率98.48%高于参照组87.88%,NRS疼痛评分(2.72±1.38)分、骨折发生率1.52%低于参照组[NRS疼痛评分(5.24±1.66)分、骨折发生率10.61%],且股骨颈(817.25±59.75)mg/cm^3、Wards三角区(649.01±52.33)mg/cm^3、大转子(733.45±59.55)mg/cm^3骨密度值均高于参照组[股骨颈(784.26±43.84)mg/cm^3、Wards三角区(594.09±49.91)mg/cm^3、大转子(701.45±49.65)mg/cm^3](P<0.05)。结论综合疗法治疗内分泌失调性骨质疏松症可有效改善患者骨密度,降低骨折风险,值得临床应用。

Objective To investigate the clinical efficacy of comprehensive therapy in the treatment of endocrine dysregulated osteoporosis.Methods A total of 132 patients with endocrine dysregulated osteoporosis admitted to our hospital from June 2016 to September 2017 were convenient selected and enrolled.The patients were divided into a reference group and a treatment group by 66 cases.The reference group took conventional therapy and the treatment group took Comprehensive treatment,comparing the clinical efficacy of the two groups of patients.Results The total effective rate of the treatment group was 98.48%higher than that of the reference group(87.88%),the NRS pain score(2.72±1.38)points,and the fracture incidence rate was 1.52%lower than the reference group[NRS pain score(5.24±1.66)points,fracture incidence rate10.61%].The femoral neck(817.25±59.75)mg/cm^3,Wards triangle(649.01±52.33)mg/cm^3,and greater trochanter(733.45±59.55)mg/cm^3 bone mineral density were higher than the reference group[femoral neck(784.26±43.84)mg/cm^3,Wards triangle(594.09±49.91)mg/cm^3,greater trochanter(701.45±49.65)mg/cm3](P<0.05).Conclusion Comprehensive therapy for endocrine disorders of osteoporosis can effectively improve bone mineral density and reduce fracture risk,which is worthy of clinical application.