影响保乳术治疗乳腺癌术后复发的相关因素探讨

Study on the Related Factors Influencing the Recurrence of Breast Cancer after Breast Conserving Surgery

目的分析影响保乳术治疗乳腺癌术后复发的相关因素。方法方便抽取该院于2008年2月—2018年2月收治的350例乳腺癌患者中131例接受保乳术治疗的乳腺癌患者为研究对象。术后随访3年,统计分析两组术后复发的相关因素。结果该组131例保乳术患者术后复发率12.98%。单因素分析结果显示:不同年龄(χ^2=4.86)、不同淋巴结转移状况(χ^2=5.06)、不同病理分型(χ^2=7.29)、不同分子分型(χ^2=10.12)保乳术患者的术后复发率差异有统计学意义(P<0.05)。多因素Logistic回归分析结果显示:影响保乳术治疗乳腺癌术后复发的相关因素包含:年龄、淋巴结转移状况、病理分型、分子分型。结论应警惕伴有低年龄、淋巴结转移、原位癌、Her-2分型等因素的乳腺癌患者,慎重选择保乳术,以减少其术后复发。

Objective To analyze the related factors affecting the recurrence of breast cancer after breast conserving surgery.Methods A total of 131 breast cancer patients who received breast conserving surgery were convenient selected from 350 breast cancer patients admitted to our hospital from February 2008 to February 2018.After 3 years of follow-up,the related factors of recurrence were analyzed.Results The recurrence rate of 131 patients with breast conserving surgery was 12.98%.Univariate analysis showed the recurrence rate after breast-conserving surgery of the patients with different ages(χ^2=4.86),different lymph node metastasis(χ^2=5.06),different pathological types(χ^2=7.29),different molecular types(χ^2=10.12),was significantly different(P<0.05).Multivariate logistic regression analysis showed that the factors affecting breast cancer recurrence after breast-conserving surgery include age,lymph node metastasis,pathological typing and molecular typing.Conclusion Breast conserving surgery should be carefully selected to reduce the recurrence of breast cancer patients with low age,lymph node metastasis,in situ cancer,Her-2 classification and other factors.