机械取栓治疗静脉溶栓无效急性中重度脑梗死对患者NIHSS评分影响分析

Effect of Mechanical Thrombectomy on Intravenous Thrombolysis in Patients with Acute Moderate to Severe Cerebral Infarction

目的观察和探究机械取栓治疗静脉溶栓无效急性中重度脑梗死对患者NIHSS评分影响。方法选择该院48例静脉溶栓治疗无效急性中重度脑梗死患者作为研究对象(收治时间范围自2017年1月—2018年12月),患者分组采用随机数字表法进行,分成研究组和对照组,各24例,对照组采用常规对症支持治疗,研究组采用急诊血管内介入机械取栓治疗,对比两组患者治疗前后的NIHSS评分、Barthel指数及治疗的总有效率。结果治疗前,两组患者NIHSS评分、Barthel指数对比差异无统计学意义(P>0.05),治疗后,NIHSS评分对比,研究组患者(11.7±2.0)分显著低于对照组(18.6±2.3)分,Barthel指数、治疗的总有效率对比,研究组患者(85.7±6.8)、(95.8%)显著高于对照组(58.4±5.2)、(79.2%),组间差异有统计学意义(t=8.864,8.817,χ^2=8.249,P<0.05)。结论采用机械取栓对静脉溶栓治疗无效急性中重度脑梗死患者治疗,不仅能提高患者整体治疗效果和降低其神经功能缺损程度,还能提升患者预后生活活动能力。

Objective To observe and explore the effect of mechanical thrombectomy on the treatment of NIHSS scores in patients with acute moderate to severe cerebral infarction.Methods Forty-eight patients with acute moderate to severe cerebral infarction who were ineffective in the treatment of intravenous thrombolytic therapy were enrolled in our hospital (from January 2017 to December 2018).The patients were divided into two groups by random number table method.There were 24 cases in the study group and the control group each.The control group received conventional symptomatic supportive treatment.The study group received emergency intravascular interventional mechanical thrombectomy.The NIHSS score,Barthel index and total effective rate of treatment were compared between the two groups.Results Before treatment,there was no statistically significant difference in NIHSS score and Barthel index between the two groups (P>0.05).After treatment,NIHSS scores were significantly lower in the study group (11.7±2.0) than in the control group (18.6±2.3) points,Barthel index,total effective rate of treatment,the study group (85.7±6.8)points,(95.8%) was significantly higher than the control group (58.4±5.2),(79.2%),statistically significant between the groups (t=8.864,8.818,χ^2=8.249,P<0.05).Conclusion The use of mechanical thrombectomy for intravenous thrombolytic therapy in patients with acute moderate to severe cerebral infarction cannot only improve the overall treatment effect and reduce the degree of neurological deficit,but also improve the prognosis of patients.