年轻宫颈癌保留生育功能患者行腹腔镜下盆腔淋巴结切除+阴式广泛宫颈切除术后临床效果及妊娠结局观察

Effect of Laparoscopic Radical Hysterectomy plus Vaginal Radical Trachelectomy in the Pregnancy Outcome for Young Cervical Cancer Patients with Fertility Function Preservation

目的:研究年轻宫颈癌保留生育功能患者行腹腔镜下盆腔淋巴结切除(LRH)+阴式广泛宫颈切除(VRT)术后的临床效果及妊娠结局。方法:抽调本院2016年1月-2017年1月进行治疗的年轻宫颈癌患者62例,根据治疗方式分为对照组(n=31)和研究组(n=31),其中对照组实施传统腹腔镜下广泛子宫切除术+盆腔淋巴结切除术,研究组实施LRH+VRT。观察研究组妊娠结局,对比两组手术与手术后相关情况、手术前后生活质量。结果:研究组手术治疗后,共妊娠25例(80.65%)。手术前两组生活质量评分情况比较,差异均无统计学意义(P>0.05)。两组手术时间、切除阴道长度比较,差异均无统计学意义(P>0.05)。手术后研究组各项生活质量评分均高于对照组(P<0.05),而研究组术中出血量与淋巴结清扫个数均优于对照组(P<0.05),研究组各项指标术后恢复情况均优于对照组,差异均有统计学意义(P<0.05)。结论:年轻宫颈癌患者可采取LRH+VRT手术方式进行治疗,手术期间各项指标情况较为良好,术后生活质量得到明显提升,术后妊娠率较高,可满足有生育需求患者,值得临床采纳。

Objective:To study the effect of laparoscopic radical hysterectomy(LRH)plus vaginal radical trachelectomy(VRT)in the pregnancy outcome for young cervical cancer patients with fertility function preservation.Method:62 young cervical cancer patients treated from January 2016 to January 2017 in our hospital were selected.According to different therapies,all patients were divided into control group(n=31)and study group(n=31).The control group was treated with conventional laparoscopic radical hysterectomy+pelvic lymphadenectomy,the study group was treated with LRH+VRT.The pregnancy outcome in the study group was observed.The operation index,postoperative conditions and the quality of life before and after surgery were compared between two groups.Result:After surgery,there were 25 pregnant cases(80.65%)in the study groups.Before surgery,there were no significant differences in quality of life score between two groups(P>0.05).The operation time and vaginal excision length between two groups were not significantly different(P>0.05).After surgery,the each life quality scores in the study group were higher than those control group(P<0.05).The intraoperative blood loss and resected lymph node number in the study group were better than those in the control group(P<0.05).The various postoperative recovery of the study group were better than those of the control group,the differences were statistically significant(P<0.05).Conclusion:For young patients with cervical cancer,LRH+VRT can be adopted for treatment.During the operation,all conditions of the patients are relatively good.It can improve the postoperative quality of life and the postoperative pregnancy rate is high.It can meet the needs of patients with fertility desire and is worthy of clinical adoption.