癌/睾丸抗原在肺癌中的研究进展

Research progress of cancer/testis antigen in lung cancer

肺癌传统的诊治手段难以达到满意的效果。寻找新的早期诊断和治疗方法迫在眉睫。很多研究表明癌/睾丸抗原(CTA)与肺癌的分期、病理类型、转移、复发等密切相关,在肺癌的免疫治疗中,CTA备受瞩目,其表达特性对肺癌诊疗方法的发展有着重要意义。现就CTA与肺癌关系的研究进展做如下综述。

Traditional diagnosis and treatment methods of lung cancer are difficult to take satisfactory effect.Therefore,it is urgent to search for new modalities for early diagnosis and novel treatment.Many studies have shown that cancer/testis antigens(CTA) correlate with cancer staging,pathology subtypes,metastasis and recurrence closely,especially in the immunotherapy of lung cancer.CTA is very high-profile and of great significance for the development of diagnosis and treatment of lung cancer because of its expression characteristics.The research progress of the relationship between CTA and lung cancer is summarized as follows.