超声实时组织弹性成像定量分析对肝脏纤维化程度的诊断和鉴别诊断价值

Quantitative analysis of real-time tissue elastography by ultrasound in the diagnosis and differential diagnosis of liver fibrosis

目的 探讨超声实时组织弹性成像定量分析对肝脏纤维化程度的诊断和鉴别价值。方法 回顾性分析60例慢性乙型肝炎患者的临床资料,均经肝穿刺活检确诊,作为研究组。选取同期到本院体检的60例健康对象,作为对照组。两组均行超声实时组织弹性成像定量分析。以肝穿刺活检病理结果为标准,判断超声实时组织弹性成像定量分析对肝脏纤维化的诊断效能。并测算两组实时组织弹性成像参数。结果 以肝穿刺活检病理结果为标准,超声实时组织弹性成像定量分析诊断灵敏度为94.74%,特异度为95.45%,准确度为95.00%;研究组平均相对应变值低于对照组,蓝色面积百分比、对比度、偏度、复杂度高于对照组,差异有统计学意义(P<0.05)。结论 超声实时组织弹性成像定量分析可为肝脏纤维化程度诊断及鉴别提供较准确依据。

Objective To investigate the value of quantitative analysis of real-time tissue elastography (RTTE) in the diagnosis and differential diagnosis of liver fibrosis. Methods The clinical data of 60 patients with chronic hepatitis B were retrospectively analyzed.All patients were diagnosed by liver biopsy and served as the research group.Sixty healthy people who came to our hospital for physical examination at the same time were selected as control group.Quantitative analysis of real-time tissue elastography was performed in both groups.Based on the pathological results of liver puncture biopsy,the diagnostic efficacy of real-time tissue elastography quantitative analysis for liver fibrosis was evaluated.The real-time tissue elastography parameters of the two groups were measured and calculated. Results According to the pathological results of liver biopsy,the sensitivity,specificity and accuracy of quantitative analysis of real-time tissue elastography were 94.74%,95.45% and 95.00%,respectively.The ARV of study group was lower than that of control group,while AREA,CONT,SKEW and COMP of study group were higher than those of control group ( P< 0.05). Conclusion Quantitative analysis of real-time tissue elastography by ultrasound can provide a more accurate method for the diagnosis and differentiation of liver fibrosis.