2型糖尿病合并高血压患者的临床特点

Analysis on the clinical characteristic of type 2 diabetic patiens with hypertension

目的 探讨2型糖尿病患者合并高血压的发生率及其相关危险因素。方法 2型糖尿病患者205例,分为高血压组(A组)和非高血压组(B组),统计分析两组的临床及实验室资料。结果 2型糖尿病合并高血压患者102例,发生率为49.8%,血压控制达标率为33.3%,使用较多的降压药物为血管紧张素受体阻滞剂和钙离子阻滞剂;与B组相比,A组的年龄、病程、收缩压、舒张压、体质指数(BMI)、空腹血糖(FBG)、餐后血糖(PBG)、糖化血红蛋白(HbA1c)、血尿酸(UA)及尿白蛋白肌酐比值(ACR)的阳性率显著增高,高密度脂蛋白胆固醇(HDL-C)水平显著降低,差异有统计学意义(P<0.05);logistic回归分析提示年龄、BMI及尿ACR是2型糖尿病合并高血压的危险因素。结论 2型糖尿病合并高血压发病率高,增龄、超重和肥胖及白蛋白尿增加2型糖尿病患者高血压发生风险。

Objective To explore the prevalence rate and the related risk factors of type 2 diabetes combined with hypertension. Methods 205 case inpatients of type 2 diabetes were selected and divided into two groups,group A (with hypertension) and group B (with no hypertension),Their clinical and laboratory data were retrospectively counted and analyzed. Results 102 case type 2 diabetic patients were combined with hypertension,the prevalence rate of hypertension in patients with type 2 diabetes was 49.8%,while the control rate of blood pressure was 33.3%,the primary administered antihypertensive drugs were angiotensin receptor blockers and calcium channel blockers.Compared with group B,age,the course of the disease,systolic blood pressure,diastolic blood pressure,BMI,fasting blood glucose,postprandial blood glucose,glycosylated hemoglobin,serum creatinine,blood uric acid,and the positive rate of urinary ACR in patients of A were much higher,while the high dentisy lipoprotein cholesterol of group A was much lower than that of group B,the difference was statistically significant ( P <0.05).logistic regression analyses showed that age,BMI and urinary ACR were the risk factors for type 2 diabetes complicated with hypertension. Conclusion The incidece rate of hypertension in patients with type 2 diabetes is high,aging,overweight or obesity and albuminuria increase the risk of type 2 diabetic patients complicated with hypertension .