空勤人员血清尿酸与心血管疾病危险因素的相关性分析

Associations between serum uric acid and risk factors of cardiovascular diseases in air crews

目的明确空勤人员血清尿酸水平与心血管疾病危险因素的关系,为空勤人员健康管理提供可靠依据。方法通过调查问卷、体格检查及实验室检查收集某疗养院238名空勤疗养人员健康体检指标,应用统计学方法分析血清尿酸与心血管疾病危险因素的关系。结果体质量指数(BMI)、收缩压、舒张压、三酰甘油(triglyceride,TG)、高密度脂蛋白胆固醇(highdensity lipoprotein cholesterol,HDL-C)、低密度脂蛋白胆固醇(low density lipoprotein cholesterol,LDL-C)/HDL-C和肌酐在尿酸水平四分位分层间比较,差异有统计学意义(P<0.05),BMI、LDL-C/HDL-C和肌酐为尿酸水平升高的独立危险因素。进一步分析发现,尿酸与BMI、收缩压、舒张压、TG、HDL-C、LDL-C/HDL-C和肌酐亦呈线性相关(P<0.05),且BMI、舒张压、TG和肌酐与其呈独立线性相关。结论空勤人员血清尿酸与心血管疾病危险因素BMI、舒张压和TG密切相关。

Objective To reveal the associations between serum uric acid and risk factors of cardiovascular diseases in air crews and provide reliable evidence for health management. Methods The general information and laboratory indexes related to cardiovascular diseases of 238 air crews were collected via questionnaires, physical examinations and laboratory examinations and statistically analyzed. Results The difference in BMI, systolic pressure, diastolic pressure, TG, HDL-C, LDL-C/HDL-C and cretinine between groups divided by quartile of serum uric acid was significantly different(P<0.05). BMI, LDL-C/HDL-C and cretinine were independent risk factors for increased serum uric acid. The relationships between serum uric acid and BMI, systolic pressure, diastolic pressure, TG, HDL-C, LDL-C/HDL-C and cretinine were linearly correlated(P<0.05). Besides, diastolic pressure, cretinine, BMI and TG were independently and linearly correlated with serum uric acid. Conclusion Diastolic pressure,BMI and TG which are correlated with cardiovascular diseases are closely related to serum uric acid.