胃癌筛查的血清标志物、内镜及影像学检查进展

Progress in gastric cancer screening with serum markers, endoscopy and imaging

我国胃癌的发病率和死亡率高,探索适应我国国情的胃癌筛查方案意义重大。通过综述胃癌高危因素、国内外筛查现状及常用筛查方法,提出依据胃癌高危因素及血清胃蛋白酶原、胃泌素-17、血清幽门螺杆菌抗体等血清标志物检测发现高危人群,在此基础上辅以内镜精细检查,是目前有效的筛查模式。

The morbidity and mortality of gastric cancer are high in China. It is of great significance to explore a screening scheme for gastric cancer that suits Chinese conditions. This article reviews the risk factors, the status of screening at home and abroad and the commonly used screening methods of gastric cancer. The articlealso recommends a screening model, in which endoscopic and imaging examination are applied for high-risk population identified by detection of the serum markers such as pepsinogen,gastrin-17 and Helicobacter pylori antibody.