幽门螺杆菌阳性患者的心理健康状态及睡眠质量调查分析

Investigation and analysis of mental health status and sleep quality in Helicobacter pylori positive infection patients

目的分析幽门螺杆菌(Hp)阳性患者心理健康状态及睡眠质量的影响因素。方法选取2018年3—9月江苏大学附属医院核医学科行13C呼气试验胃部不适的患者208例,采用胃肠道症状表、Kessler10量表及匹兹堡睡眠质量指数(PSQI)量表进行问卷调查。结果单因素分析结果显示,Kessler10量表与性别、饮酒、喜食辛辣、目前Hp情况、腹痛、腹胀、反酸、烧心、嗳气、胃肠道严重程度、胃肠道发作频率有相关性(P<0.05);多因素分析结果显示,目前Hp情况、胃肠道发作频率是影响因素(P<0.05)。单因素分析显示,PSQI量表与性别、喜食辛辣、目前Hp情况、腹痛、腹胀、反酸、腹泻、嗳气、胃肠道严重程度、胃肠道发作频率有相关性(P<0.05);多因素分析结果显示,性别、目前Hp情况、胃肠道发作频率是影响因素(P<0.05)。结论幽门螺杆菌感染影响患者心理健康状态及睡眠质量。

Objective To analyze the influencing factors of mental health status and sleep quality in patients with Helicobacter pylori (Hp) positive infection. Methods Totally 208 patients with gastrointestinal discomfort who underwent 13 C breath test in the Department of Nuclear Medicine of Affiliated Hospital of Jiangsu University from March to September 2018 were investigated by Gastrointestinal Symptom Scale, Kessler 10 Scale and Pittsburgh Sleep Quality Index (PSQI). Results Univariate analysis showed that Kessler 10 scale was correlated with gender, alcohol consumption, appetite for spicy food, current Hp status, abdominal pain, abdominal distention, acid reflux, heartburn, belching, gastrointestinal severity and frequency of gastrointestinal attacks ( P <0.05), and multivariate analysis showed that the current Hp status and frequency of gastrointestinal attacks were the influencing factors ( P <0.05). Univariate analysis showed that the PSQI scale was correlated with gender, appetite for spicy food, current Hp status, abdominal pain, abdominal distension, acid reflux, diarrhea, belching, gastrointestinal severity and frequency of gastrointestinal attacks ( P <0.05), and multivariate analysis showed that gender, current Hp status and frequency of gastrointestinal attacks were influencing factors ( P <0.05). Conclusion Hp infection can affect patient′s mental health status and sleep quality.