止颤汤合柴胡加龙骨牡蛎汤治疗帕金森病合并抑郁症42例

Zhichan Decoction and Chaihu Longgu Muli Decoction in Treating Parkinson’s Disease Complicated with Depression for 42 Cases

目的探究对帕金森合并抑郁患者实施止颤汤合柴胡加龙骨牡蛎汤化裁治疗的临床效果,从而为临床提供指导。方法随机将2016年7月—2018年4月收治的84例帕金森合并抑郁患者分为观察组,各42例。观察组应用止颤汤合柴胡加龙骨牡蛎汤化裁治疗、对照组接受临床常规治疗。比较2组治疗前后负面情绪、治疗效果、帕金森病症评分。结果比较2组患者临床治疗总有效率,观察组治疗总有效率40(95.24%)例高于对照组治疗总有效率32(76.19%)例,组间对比差异性显著P<0.05;治疗前2组患者负面情绪评分与帕金森症状评分比较无明显差异P>0.05,治疗后观察组抑郁评分、焦虑评分、帕金森病症状评分均低于对照组各项评分,2组对比统计学意义存在P<0.05。结论针对帕金森病合并抑郁患者应用止颤汤合柴胡加龙骨牡蛎汤化裁治疗,其临床效果显著,不良反应较低,用药安全可靠。

Objective To explore the clinical effect of Zhichan decoction and Chaihu Longgu Muli decoction in treating Parkinson's disease complicated with depression, so as to provide guidance for the clinic.Methods From July 2016 to April 2018, 84 patients with Parkinson's disease complicated with depression in our hospital were randomly divided into observation group (42 cases, treated with Zhichan decoction and Chaihu Longgu Muli decoction) and control group (42 cases received clinical routine treatment).Negative emotions, treatment effects, and Parkinson's disease scores were compared before and after treatment.Results The total effective rate of the two groups was compared.The total effective rate of the observation group was 95.24%(40), which was higher than 76.19%(32) of the control group.The difference between the groups was significant P<0.05.There was no significant difference between the scores of Parkinson's symptoms P>0.05.After treatment, the scores of depression, anxiety score and Parkinson's disease of the observation group were lower than those of the control group.There had statistical significance P<0.05.Conclusion Zhichan decoction and Chaihu Longgu Muli decoction in treating Parkinson's disease complicated with depression has a significant clinical effect, its adverse reactions are low, and the medication is safe and reliable.