利培酮治疗老年帕金森伴精神障碍效果分析

Clinical Efficacy of Risperidone in the Treatment of Elderly Patients With Parkinson’s Disease and Mental Disorders

目的探讨利培酮与氟哌啶醇治疗老年帕金森伴精神障碍患者的临床价值,以期指导临床下一步用药。方法随机将我院2017年6月-2018年6月收治的70例帕金森伴精神障碍老年患者分为两组,每组35例。观察组给予利培酮治疗,对照组给予氟哌啶醇治疗。比较两组临床疗效。结果观察组PANSS评分、MMSE评分、UPDRS评分、HAMD评分以及不良反应等指标明显优于对照组,差异显著(P<0.05)。结论利培酮治疗老年帕金森伴精神障碍效果显著,能够明显改善患者的认知功能以及精神障碍,提高了患者的生活质量,保障了患者的身体健康,值得临床中推广应用。

Objective To investigate the clinical value of risperidone and haloperidol in the treatment of elderly patients with Parkinson’s disease and mental disorders, in order to guide the next step in clinical use. Methods Seventy elderly patients with Parkinson’s disease and mental disorders admitted to our hospital from June 2017 to June 2018 were randomly divided into two groups, 35 cases in each group. The observation group was treated with risperidone and the control group was treated with haloperidol.The clinical efficacy of the two groups was compared. Results The PANSS score, MMSE score, UPDRS score, HAMD score and adverse reactions of the observation group were significantly better than the control group,and the difference was significant(P < 0.05). Conclusion Risperidone is effective in the treatment of elderly patients with Parkinson’s disease and mental disorders. It can significantly improve the cognitive function and mental disorders of patients, improve the quality of life of patients, and ensure the health of patients. It is worthy of clinical application.