急性单发性脑梗死与继发性不宁腿综合征的相关性

Relationship of acute single cerebral infarction and secondary restless legs syndrome

目的分析在急性单发性脑梗死(ASCI)患者中,梗死部位与继发性不宁腿综合征(SRLS)的关系。方法回顾性连续收集ASCI患者556例,收集人口统计学特征、化验结果、影像资料、并存疾病、ASCI临床特征等资料,并分为SRLS组和非SRLS组。对两组进行比较,采用单因素分析探讨ASCI患者SRLS的相关因素,多因素分析探讨ASCI患者SRLS的独立相关因素。结果纳人的556例ASCI患者中,26例(4.68%)并发SRLS。单因素分析显示,尿酸与SRLS发病相关(P<0.05),丘脑及脑桥部位ASCI患者SRLS发病率较髙,纳人多因素分析显示,ASCI位于丘脑(OR=5.81,P<0.05)和脑桥(0R=2.65,P<0.05)是并发SRLS的独立相关因素。结论在ASCI患者中,梗死部位与SRLS发病相关,丘脑和脑桥部位ASCI可能是SRLS的独立预测因素。

Objectives To analyze the relationship between the location of acute single cerebral infarction (ASCI) and secondary restless leg syndrome (SRLS). Methods The data of 556 continuous patients with ASCI were collected retrospectively, including demographic characteristics, laboratory results, imaging data, coexisting diseases, clinical characteristics of ASCI. All the patients were divided into SRLS group and non-SRLS group. Comparing between the two groups, univariate analysis was used to explore the related factors of SRLS in patients with ASCI, and multivariate analysis was used to explore the independent related factors of SRLS in patients with ASCI. Results Of the 556 ASCI patients included, 26 (4.68%) suffered SRLS. Univariate analysis revealed uric acid was associated with the morbidity of SRLS ( P < 0.05), and the incidence of SRLS was higher in thalamic and pons ASCI patients. Multivariate analysis revealed that ASCI occurring in the location of thalamus (OR=5.81, P < 0.05) and pons (OR=2.651 P < 0.05) are independent predictors for SRLS. Conclusions In patients with ASCI, the location of infarction is associated with the morbidity of SRLS, and ASCI occurring in the thalamus and pons may be independent predictors for SRLS.