围产儿出生缺陷监测分析与干预措施

Monitoring Analysis of Perinatal Birth defects and Intervention Measures

目的研究围产儿出生缺陷发生率与干预现状,并提出对应干预措施。方法回顾性分析2015年10月—2018年10月本市三家省级出生缺陷监测医院围产儿出生缺陷资料,根据《中国出生缺陷医院监测方案》中23类出生缺陷的定义、诊断标准以及特征实施临床检测。分析缺陷发生率,缺陷发生于产妇年龄关系及婚检关系。结果缺陷发生率为2.26%,3年间呈上升趋势。产妇年龄>35岁时缺陷发生率最高,差异有统计学意义(P<0.05);婚检组围产儿出生缺陷发生率为1.01%,低于未婚检组(5.72%),差异具有统计学意义(P<0.05)。结论婚检与适龄生产可降围产儿出生缺陷发生率。

Objective To study the incidence and intervention status of perinatal birth defects, and put forward corresponding intervention measures. Methods The data of perinatal birth defects of perinatal babies in three provincial monitoring hospitals of birth defects in this city from October 2015 to October 2018 were retrospectively analyzed, and clinical tests were conducted according to the definition, diagnostic criteria and characteristics of 23 types of birth defects in the monitoring program of China birth defect hospitals. The incidence of defects was analyzed, and the defects occurred in the relationship between maternal age and premarital examination. Results The incidence of defect was 2.26%, which showed an upward trend in three years. The incidence of defects was the highest when the puerpera was older than 35 years old (P < 0.05). The incidence of perinatal birth defects in premarital examination group was 1.01%, lower than that in unmarried examination group (5.72%), the difference was statistically significant (P < 0.05). Conclusion The rate of birth defects of perinatal infants can be reduced by premarital examination and ageappropriate birth.