老年自身免疫性肝炎的临床检验特点分析

Analysis of Clinical Characteristics of Elderly Autoimmune Hepatitis

目的讨论老年自身免疫性肝炎的临床检验特点。方法于2017年1月—2018年9月,选取我院收治的100例自身免疫性肝炎患者作为研究对象,而后以患者年龄差异将其分为对照组(年龄≤60岁)与研究组(年龄>60岁),而后对两组患者的生化指标与免疫指标进行监测。结果以临床中各项指标的正常值作为标准,研究组患者中WBC、MCV、MCH、HGB、PLT指标均不在正常范围内,属于异常指标;对照组的各指标均在正常范围内,研究组与对照组的各项指标比较,差异具有统计学意义(P<0.05);研究组患者的各项肾脏功能指标高于对照组(P<0.05),且属于异常指标;研究组患者的抗核抗体阳性率与ENA阳性率高于对照组(P<0.05)。结论研究组中年龄偏大,老年人居多,所以各个数据指标与正常指标进行对比相差较大,老年患者发生自身免疫性肝炎的机率明显高于非老年患者,在该病的诊断过程中应尤其注意老年患者的各项检查结果,以为其提供科学、合理的治疗方案。

Objective To discuss the clinical characteristics of elderly autoimmune hepatitis. Methods From January 2017 to September 2018, 100 patients with autoimmune hepatitis in our hospital were selected as the study subjects. The patients were divided into control group (age ≤ 60 years) and research group (age > 60 years). Then the biochemical and immune indexes of the two groups were monitored. Results With the normal values of clinical indicators as the standard, WBC, MCV, MCH, HGB and PLT indicators in the study group were not within the normal range, which belonged to abnormal indicators. The indexes of the control group were within the normal range, and there was a significant difference between the study group and the control group (P < 0.05). The renal function indexes of the study group were higher than those of the control group (P < 0.05), and belonged to abnormal indexes. The positive rates of ANA and ENA in the study group were higher than those in the control group (P < 0.05). Conclusion In the study group, older people are the majority, so there is a big difference between the data indicators and normal indicators. The incidence of autoimmune hepatitis in elderly patients is significantly higher than that in non-elderly patients. In the process of diagnosis of the disease, we should pay special attention to the results of various examinations of elderly patients, so as to provide scientific and reasonable treatment for them.