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原发性醛固酮增多症筛查中化学发光法测定血浆醛固酮和肾素浓度的价值分析及参考区间

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摘要 目的探讨原发性醛固酮增多症中化学发光法测定血浆醛固酮(PAC)与肾素(PRC)浓度的价值及参考区间。方法以30例高血压患者为研究对象,使用化学发光法检测器卧位、立位2 h的PAC及PRC,计算PAC与PRC比值(ARR)并与患者病理诊断结果进行对比。结果 30例高血压患者中有原醛患者11例、原发性高血压患者16例、其他内分泌性高血压患者3例。原醛患者立位PAC、ARR与原发性高血压患者及其他内分泌性高血压患者相比明显升高,同时立位PRC明显降低,对比存在明显差异(P<0.05)。同时原醛患者卧位PAC、ARR明显高于其他两组患者(P<0.05),卧位PRC与其他两组患者相比明显降低,有统计学意义(P<0.05)。结论化学发光法对检测原醛患者立位、卧位的PAC以及PRC浓度均有积极作用,可用于原醛患者的筛查过程中。
作者 梁懿玑
出处 《心电图杂志(电子版)》 2019年第3期122-123,共2页 Journal of Electrocardiogram(Electronic Edition)
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