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奥卡西平和丙戊酸钠治疗癫痫效果的对比分析

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摘要 目的:探究奥卡西平和丙戊酸钠分别治疗癫痫的效果分析。方法:选取2016年2月至2017年2月在我院治疗的癫痫患者68例,随机分为I组(34例)和II组(34例)。I组患者采用奥克西平治疗,II组采用丙戊酸钠治疗,连续治疗6个月,观察两组患者治疗前后血清同型半胱氨酸(Hcy)、超敏C反应蛋白(hs-CRP)、非对称性二甲基精氨酸(ADMA)表达水平,认知功能和生存质量。结果:治疗后两组患者Hcy、hs-CRP、ADMA表达水平均显著高于治疗前(P<0.05),组间比较无统计学差异(P>0.05);治疗后,I组MMSE评分显著高于II组,QOLIE评分显著低于II组(P<0.05),两组不良反应发生率无统计学差异(P<0.05)。结论:奥卡西平可有效改善患者认知功能和生活质量,其副反应和对血清Hcy、hs-CRP、ADMA影响与丙戊酸钠相似。
作者 丛日楠
出处 《医学食疗与健康》 2019年第5期5-6,共2页 Medical Diet and Health
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