缬沙坦联合硝苯地平控释片治疗原发性高血压的疗效观察

Therapeutic Effect of Valsartan Combined with Nifedipine Controlled Release Tablets in the Treatment of Essential Hypertension

目的分析缬沙坦联合硝苯地平控释片治疗原发性高血压的临床疗效。方法选取本院2016年12月~2017年12月收治的180例高血压患者作为研究对象,计算机随机分为两组,两组各90例。对照组患者给予硝苯地平进行治疗,实验组患者在对照组基础上联合缬沙坦进行治疗,比较两组临床疗效。结果实验组患者头痛、下肢水肿、恶心等并发症总发生率明显较低,经过治疗后实验组治疗有效率高于对照组,两组比较差异显著(P <0.05)。结论采用缬沙坦联合硝苯地平进行治疗能够提高治疗效果和安全性,值得临床应用。

Objective To analyze the clinical efficacy of valsartan combined with nifedipine controlled release tablets in the treatment of primary hypertension. Methods 180 hypertensive patients treated in our hospital from December 2016 to December 2017 were selected as study subjects and they were randomLy divided into two groups ,with 90 cases in each group. The control group was treated with nifedipine, and the experimental group was treated with valsartan on the basis of control group. Results The total incidence of complications in the control group such as headache, lower limb edema and nausea was significantly lower than that in the experimental group. After treatment, the treatment efficiency of experimental group was significantly higher than that of the control group. Conclusion Valsartan combined with nifedipine can improve the efficacy and safety of treatment,which is worthy of wide application in clinical treatment.