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不同炎症表型哮喘常用生物学标志物进展 被引量:8

Progress in common biomarkers for different inflammatory phenotype asthma
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摘要 支气管哮喘是由多种细胞及炎症介质参与引起的综合征。支气管哮喘根据炎症介质参与程度不同分为不同的炎症表型,其各自又有相对特异的生物学标志物,通过对这些生物学标志物的监测进而了解、评估哮喘的控制情况,可指导哮喘针对性治疗和更完善的管理。 Bronchial asthma is a syndrome caused by the involvement of a variety of cells and inflammatory mediators. Bronchial asthma is divided into different inflammatory phenotypes according to the degree of involvement of inflammatory mediators. Each of them has relatively specific biomarkers. By monitoring these biomarkers, the control situation of asthma can be understood and evaluated to guide targeted treatment of asthma and more perfect management.
作者 屈小雪 刘雅莉 王健美 张薇 QU Xiaoxue;LIU Yali;WANG Jianmei;ZHANG Wei(Department of Respiration, First Affiliated Hospital of Harbin Medical University, Harbin 150001, China)
出处 《临床与病理杂志》 2019年第6期1349-1355,共7页 Journal of Clinical and Pathological Research
关键词 哮喘 炎症表型 生物学标志物 asthma inflammatory phenotype biomarkers
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  • 1吴晓东,施毅.气道防御屏障[J].中国呼吸与危重监护杂志,2011,10(3):301-304. 被引量:7
  • 2罗炜,赖克方,陈如冲,陈桥丽,钟南山.广州地区诱导痰细胞学正常参考值的建立[J].国际呼吸杂志,2007,27(16):1213-1215. 被引量:29
  • 3中华医学会呼吸病学分会哮喘学组.咳嗽的诊断与治疗指南(2009版)[J].中华结核和呼吸杂志,2009,3(2):407-413.
  • 4Gibson PG. Inflammatory phenotypes in adult asthma : clinical applications[J].Clin Respir J, 2009,3 (4) : 198-206. DOI: 10. 1111/i. 1752-699X. 2009. 00162. x.
  • 5Simpson JL, Scott R, Boyle MJ, et al. Inflammatory subtypes in asthma: assessment and identification using induced sputum [J].Respirology, 2006,11(1) : 54-61. DOI: 10. 1111/j. 1440-1843. 2006. 00784. x.
  • 6Global Initiative for Asthma (GINA):Global strategy for asthma management and prevention; 2014. www. ginasthma. org. [Z]. 2014.
  • 7Pavord ID, Brightling CE, Woltmann G, et al. Non- eosinophilic eortieosteroid unresponsive asthma [J].Lancet, 1999,353(9171):2213 2214. DOI:10.1016/S0140-6736(99) 01813-9.
  • 8Wood LG, Baines KJ, Fu J, et al. The neutrophilic inflammatory phenotype is associated with systemic inflammation in asthma[J]. Chest, 2012,142 ( 1 ) : 86-93. DOI : 10.13?8/chest. 11 1838.
  • 9Haldar P, Pavord ID. Noneosinophilic asthma: a distinct clinical and pathologic phenotype [J]. J Allergy Clin Immunol, 2007, 119 (5): 1043-1052, 1053-1054. DOI: 10. 1016/j. jaci. 2007.02. 042.
  • 10Chu DK, Al-Garawi A, Llop Guevara A, et al. Therapeutic potential of anti-IL-6 therapies for granulocytie airway inflammation in asthma [J]. Allergy Asthma Clin lmmunol, 2015,11(1) :14.DOI:10. 1186/s13223-015-0081-1.

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