3.0T磁共振成像动态增强联合扩散加权成像在子宫内膜癌诊断中的应用价值

Clinical effect of dynamic 3.0 T magnetic resonance imaging enhancement combined with diffusion-weighted imaging in diagnosis of endometrial cancer

目的探讨子宫内膜癌诊断中采用3.0T磁共振成像动态增强(DCE-MRI)联合扩散加权成像(DWI)的临床效果。方法回顾性分析2017年2月至2018年4月在运城市中心医院就诊的92例子宫内膜癌患者的临床资料,所有患者均行DCE-MRI联合DWI检查,并以病理诊断结果为金标准,比较DCE-MRI联合DWI检查与DCE-MRI单独诊断子宫内膜癌患者的病理分期、宫颈侵犯结果及诊断价值。结果DCE-MRI联合DWI检查子宫内膜癌病理分期及宫颈侵犯的准确性均高于DCE-MRI单独检查,差异有统计学意义(P<0.05);DCE-MRI联合DWI检查子宫内膜癌病理分期的敏感性、特异性、阳性预测值及阴性预测值均高于DCE-MRI检查,差异有统计学意义(P<0.05);DCE-MRI联合DWI检查子宫内膜癌宫颈侵犯的敏感性及阴性预测值均高于DCE-MRI单独检查,差异有统计学意义(P<0.05)。结论3.0TDCE-MRI联合DWI检查可准确评估子宫内膜癌患者术前病理分期及宫颈侵犯情况,为手术方案的制定提供依据。

Objective To investigate the effect of dynamic 3.0 T magnetic resonance imaging enhancement(DCE-MRI)combined with diffusion-weighted imaging(DWI)in the diagnosis of endometrial cancer.Methods The clinical data of 92 patients with endometrial cancer admitted in Yuncheng Central Hospital from February 2017 to April 2018 were retrospectively analyzed.All patients underwent DCE-MRI combined with DWI.The pathological diagnosis as the gold standard,the pathological staging,cervical invasion and diagnostic value of DCE-MRI combined with DWI and DCE-MRI in the diagnosis of endometrial cancer were compared.Results The accuracy of pathological staging and cervical invasion of endometrial cancer by DCE-MRI combined with DWI was significantly higher than that of DCE-MRI alone,and the difference was statistically significant(P<0.05).Endometrial cancer was detected by DCE-MRI combined with DWI.The sensitivity,specificity,positive predictive value and negative predictive value of pathological staging were higher than those of DCE-MRI,and the difference was statistically significant(P<0.05).The sensitivity of DOE-MRI combined with DWI in detecting cervical invasion of endometrial cancer.The negative predictive value was higher than that of DCE-MRI alone,and the difference was statistically significant(P<0.05).Conclusions 3.0 T DCE-MRI combined with DWI can accurately assess the preoperative pathological stage and cervical invasion of endometrial cancer patients,and provide a basis for the formulation of surgical plan.