摘要
Pafuranones A(1)and B(2),a pair of new epimeric polyketide dimers,were isolated from the fungus Paraconiothyrium sp.OUCMDZ-3316 associated with the marine algae Enteromorpha prolifera.Their structures,including absolute configurations,were fully elucidated based on spectroscopic analysis,calculated ECD,and chemical methods.Pafuranones A(1)and B(2)possess a rare dimeric furanone skeleton,which might be formed through a conjugate addition of the monomeric units followed by an intramolecular cyclization.
Pafuranones A(1) and B(2), a pair of new epimeric polyketide dimers, were isolated from the fungus Paraconiothyrium sp. OUCMDZ-3316 associated with the marine algae Enteromorpha prolifera. Their structures, including absolute configurations, were fully elucidated based on spectroscopic analysis,calculated ECD, and chemical methods. Pafuranones A(1) and B(2) possess a rare dimeric furanone skeleton, which might be formed through a conjugate addition of the monomeric units followed by an intramolecular cyclization.
基金
financially supported by the National Natural Science Foundation of China(Nos.41876172,41806086,U150122141376148&U1606403)
the Fundamental Research Funds for the Central Universities(No.201841006)
