阻塞性睡眠呼吸暂停低通气综合征与颈动脉内膜中层厚度关系的研究进展

Research progress on the relationship between obstructive sleep apnea hypopnea syndrome and carotid intima-media thickness

阻塞性睡眠呼吸暂停低通气综合征(OSAHS)以夜间反复低氧血症、高碳酸血症为特点。近年来发现OSAHS与中风、心力衰竭等动脉粥样硬化性心血管疾病(ASCVD)发病密切相关。而颈动脉内膜中层厚度(CIMT)可预测ASCVD。故研究OSAHS与CIMT对于预防OSAHS患者动脉粥样硬化(As),甚至ASCVD意义重大。本文介绍了OSAHS的流行病学、OSAHS导致IMT增厚的机制及相关治疗,为干预OSAHS患者的动脉粥样硬化进展提供参考和依据。

Obstructive sleep apnea hypopnea syndrome( OSAHS) is characterized by recurrent hypoxemia and hypercapnia at night. Recent fingdings show that OSAHS is closely associated with atherosclerosis cardiovascular disease (ASCVD) such as stroke,heart failure. And carotid intima-media thickness( CIMT) can predict ASCVD. So it is significant for preventing atherosclerosis( As) in OSAHS patients to study the relationship between IMT and OSAHS. This review summarized the recent research progress on the relationship between obstructive sleep apnea hypopnea syndrome and carotid intima-media thickness, including human epidemiological and related mechanism studies and related treatments. It can provide a background reference for interrupting the progress of As in OSAHS patients.