内镜色素染色对食管癌、胃癌的早期诊断价值分析

Analysis on the Value of Endoscopic Pigment Staining in the Early Diagnosis of Esophageal Cancer and Gastric Cancer

目的分析内镜色素染色对食管癌、胃癌的早期诊断价值。方法选取我院2015年1月至2018年6月收治的疑似食管癌、胃癌患者300例作为观察对象,针对300例疑似食管癌、胃癌患者实施内镜色素染色检测,将检测结果与最终的临床病理学诊断结果进行对比分析,分析内镜色素染色对于食管癌、胃癌的早期诊断价值。结果经内镜食管黏膜复方碘液染色诊断的疑似患者115例,有不着色区域明显淡染区患者51例,单纯增生及炎症患者17例,不典型增生患者20例, Barrett食管患者10例,食管癌患者4例。经内镜胃美蓝染色诊断的疑似患者185例,有不着色区域明显淡染区的患者163例,单纯增生及炎症患者87例,不典型增生患者10例,胃癌患者11例(其中原位癌2例),肠上皮化生患者55例;内镜色素染色结果与临床病理学结果比较,差异无统计学意义(P>0.05)。结论内镜色素染色对于食管癌、胃癌的诊断效果较为显著,对于病变的定性具有较高的临床应用价值,有利于疾病的诊断及鉴别诊断,为患者的临床治疗提供有力的参考依据。

Objective To analyze the value of endoscopic pigment staining in the early diagnosis of esophageal cancer and gastric cancer. Methods 300 patients with suspected esophageal cancer or gastric cancer in our hospital from January 2015 to June 2018 were selected as observation objects. 300 patients with suspected esophageal cancer or gastric cancer were performed with endoscopic pigment staining. The test results were compared with the final clinical pathology diagnosis, and the early diagnosis value of endoscopic pigment staining for esophageal cancer or gastric cancer were analyzed. Results 115 suspected patients were diagnosed by endoscopic esophageal mucosa compound iodine solution staining, including 51 patients with uncolored area or obviously lightly dyed area, 17 patients with simple hyperplasia and inflammation, 20 patients with atypical hyperplasia, 10 patients with Barrett esophagus and 4 patients with esophageal cancer. 185 patients were diagnosed by endoscopic gastromethylene blue staining, including 163 patients with uncolored area or obviously lightly dyed area, and 87 patients with simple hyperplasia and inflammation, 10 patients with atypical hyperplasia, 11 patients with gastric cancer (2 cases of carcinoma in situ) and 55 patients with intestinal metaplasia. No significant difference was found between the endoscopic pigment staining results and the clinical pathological results (P >0.05). Conclusions Endoscopic pigment staining has a significant diagnostic effect on esophageal cancer and gastric cancer. It has a high clinical value for the qualitative diagnosis of lesions, and is conducive to the diagnosis and differential diagnosis of diseases, and provides a powerful reference for clinical treatment of patients.