改良“三明治”法注射栓塞联合内镜套扎术治疗食管胃底静脉曲张出血的近远期疗效观察

Observation on the Short-Term Efficacy and Long-Term Efficacy of Modified " Sandwich" Injection Embolization Combined with Endoscopic Ligation for the Treatment of Esophagogastric Variceal Hemorrhage

目的探讨改良"三明治"法注射栓塞联合内镜套扎术治疗食管胃底静脉曲张出血的效果。方法将本院2016年3月至2018年3月收治的60例食管胃底静脉曲张出血患者随机分成观察组(n=30)与对照组(n=30),对照组使用单纯内镜套扎术治疗,观察组使用改良"三明治"法注射栓塞联合内镜套扎术治疗,观察两组的近远期疗效。结果近期疗效上,观察组的治疗总有效率为93.33%,显著高于对照组的73.33%(P<0.05);远期随访结果上,观察组的再出血率、复发率及并发症发生率分别为3.33%、0.00%、6.67%,对照组分别为20.00%、13.33%、26.67%,组间差异有统计学意义(P<0.05)。结论对于食管胃底静脉曲张出血患者,采取改良"三明治"法注射栓塞联合内镜套扎术治疗,可取得显著的近远期疗效,值得推广。

Objective To investigate the effect of modified "sandwich" injection embolization combined with endoscopic ligation for the treatment of esophagogastric variceal hemorrhage. Methods 60 patients with esophagogastric variceal hemorrhage in our hospital from March 2016 to March 2018 were randomly divided into observation group (n = 30) and control group (n = 30). The control group was treated with simple endoscopic ligation, and the observation group was treated with modified "sandwich" injection embolization combined with endoscopic ligation. The short-term efficacy and long-term efficacy of the two groups were observed. Results In terms of short-term efficacy, the total effective rate of treatment in the observation group was 93.33%, significantly higher than 73.33% in the control group (P <0.05). In terms of long-term follow-up results, the re-bleeding rate, recurrence rate and incidence of complications in the observation group was 3.33%, 0.00% and 6.67% respectively, significantly lower than 20.00%, 13.33% and 26.67% in the control group (P <0.05). Conclusions For patients with esophagogastric variceal hemorrhage, modified "sandwich" injection embolization combined with endoscopic ligation can achieve significant short-term efficacy and long-term efficacy, which is worthy of promotion.