骨关节炎生物标志物研究进展

Progress in research on biomarkers of osteoarthritis

骨关节炎(OA)是一种世界性的常见病和多发病,随着人口老龄化的日益严重,OA的发病率也越来越高,是造成老年人运动障碍的首要疾病,已成为一种严重的公共卫生问题。OA生物标志物研究是深入探讨其病因、发病机制、早期诊断以及有效治疗药物的重要手段。故作者就近年来OA最新生物标志物和疑似生物标志物的研究状况进行了综述。

Osteoarthritis (OA) is a worldwide common and frequently-occurring disease,with increasing age of the population,the incidence of OA is also increasing;it is the leading cause of dyskinesia in the elderly and has become a serious public health problem.OA biomarker research is an important means to further explore its etiology,pathogenesis,early diagnosis and effective treatment of OA.Therefore,the authors reviewed the research status of the latest biomarkers and suspected biomarkers of OA in recent years.