摘要
帕金森病(Parkinson′s disease, PD)是一种以运动迟缓、静止性震颤和肌强直为主要临床特点的神经退行性疾病,其病理生理基础为锥体外系中黑质纹状体多巴胺能神经元的变性[1,2]。PD在临床表现及病理方面均与非典型帕金森综合征(atypical Parkinsonism, APS)有相当的重叠性,后者包括多系统萎缩(multiple system atrophy, MSA)、进行性核上性麻痹(progressive supranuclear palsy, PSP)和皮质基底节变性(corticobasal degeneration, CBD)等疾病。目前PD的诊断和治疗主要基于对患者的临床评估和长期随访。
作者
左传涛
葛璟洁
蒋承峰
管一晖
Zuo Chuantao;Ge Jingjie;Jiang Chengfeng;Guan Yihui(PET Center, Huashan Hospital, Fudan University, Shanghai 200235, China;Institute of Medical Function and Molecular Imaging, Fudan University, Shanghai 200040, China;National Center for Clinical Medicine of Geriatric Diseases, Shanghai 200040, China;Fudan University Molecular Imaging and Translational Medicine Center of Integrated Traditional Chinese and Western Medicine, Shanghai 200040, China;Department of Nuclear Medicine, Kunshan Hospital Affiliated to Jiangsu University, Kunshan 215300, China)
出处
《中华核医学与分子影像杂志》
CAS
北大核心
2019年第6期321-324,共4页
Chinese Journal of Nuclear Medicine and Molecular Imaging
